New York -- which avoided its first 1-4 start since 2006 with Tuesday's 5-4 win in 12 innings -- will turn to CC Sabathia, who hopes to rebound from a disappointing Opening Day start and record his first victory of the year, facing a team against which he owns a career 16-2 record and 2.74 ERA.
Sabathia, who allowed five earned runs over six innings on Friday against the Rays, acknowledged that he and pitching coach Larry Rothschild went to work to iron out any leftover kinks from last week's start.
"I just threw my normal bullpen [session]," Sabathia said. "I got with Larry and tried to make sure that I could throw my fastball over the plate. I'm sure Larry watched the tape; I don't watch much video. In the bullpen, we just talked about my tempo and my delivery. It was good the other day, so I would expect it to be good tomorrow."
While some pressure has been relieved following back-to-back Yankees wins, the onus remains on Sabathia to find his rhythm. Nevertheless, the left-hander is taking a balanced approach into Wednesday's start.
"You want to get back out there, but whether it's a good start or a bad start, once I leave the field, I let it go," Sabathia said. "I can't take anything out there with me. Pitching bad against Tampa is not going to help me out here against the Orioles. I'll go out and try to throw my fastball, have my fastball command and throw everything off of that."
Conversely, Jake Arrieta returns to the hill, coming off an excellent season debut. The third-year O's right-hander blanked the Twins over seven innings, allowing two hits and striking out four.
In his 42nd career outing, Arrieta will face a familiar foe on Wednesday, facing the Yankees for the sixth time -- more than he's pitched against any other opponent. Arrieta is 2-1 with a 3.99 ERA in five career starts against New York, with 24 strikeouts and 15 walks over 29 1/3 innings. His final start last season came in New York on July 31, when he allowed four runs (two earned) over five innings with four strikeouts and six walks.
Yankees: Jeter off to a hot start
Derek Jeter hit his 25th career leadoff home run on Tuesday night, passing Rickey Henderson to claim a franchise record. The home run punctuated a hot start to 2012 for Jeter, who is hitting .391 (9-for-23) through five games this season. Jeter hit just .167 (3-for-22) with one RBI through the first five games of 2011 and did not hit his first home run last year until May 8.
Orioles: Wieters solves Yanks pitching
Matt Wieters got off to a slow start against the Twins last week, recording just one hit in his first 11 at-bats. However, the Orioles backstop found his swing when the Yankees came to Camden Yards. Wieters recorded five hits in a row spanning Monday and Tuesday, including his first home run of the season. It has been a change of pace for Wieters, who entered the series just a .183 lifetime hitter against New York.
Wednesday marks the 100th anniversary of the last Yankees home opener at Hilltop Park, in their final season as the New York Highlanders. The Yankees played at the Polo Grounds from 1913-22 before moving into Yankee Stadium in '23.
Adam Jones boasts a career .333 average (11-for-33) with two home runs and nine RBIs against Sabathia.